Articles & Clinical Papers
An Explanation of Siascopy™
Author: Mark Chellingworth
Abstract: Siascopy uses light to image skin. It is based on a thorough understanding of the skin’s anatomy: its structure and constituent materials. These constituent materials are haemoglobin, melanin, collagen and dermal melanin. They are referred to as chromophores because they interact with light and thus give skin its colour.
Clinical Application of Spectrophotometric Intracutaneous Analysis
Authors: Marc Moncrieff, Symon Cotton, Ela Claridge, Per Hall.
Abstract: Spectrophotometric Intracutaneous Analysis (SIA) is a rapid, non-invasive scanning technique where a Siascope is used to analyse light reflected from the skin in the visible and infrared spectra. Complex algorithms return SIAgraphs that contain high-resolution information regarding the in vivo epidermal and dermal melanin, vasculature and the collagen content of the papillary dermis within the lesion.
A Comparison Between Dermatoscopy and Spectrophotometric Intracutaneous Analysis (Siascopy) for the Diagnosis of Melanoma
Authors: Mr J Powell, Mr M Moncrieff, Mr P Hall
Abstract: This study was designed to assess the ability of the Siascope and a simple scoring system at detecting malignant melanoma and to compare this directly with the 7-point checklist described by Argenziano.
Siascope as a Possible Adjunct to Dermatoscopy
Authors: R. Schiffner, U. Lepski, M. Moncrieff, S. Cotton
Abstract: The Siascope is a device which examines a 12mmx12mm area of in-vivo skin returning information regarding its structure and composition. It utilizes spectral bands of light including visible and infrared returning SIAgraphs showing the distribution and quantity of: collagen within the papillary dermis; blood; melanin and the presence of melanin in the papillary dermis.
Spectrophotometric Intracutaneous Analysis (SIA) for the Diagnosis of Early Malignant Melanoma – Dermal Melanin Depth and Distribution
Authors: Mr J Powell, Dr S Cotton, Mr M Moncrieff, Mr P Hall
Abstract: Siascopy is a multispectral imaging technique that rapidly returns high-resolution information regarding the skin. Simple Siascopic features for the detection of melanoma have been identified and include: melanin in the papillary dermis, central displacement of papillary blood supply with a peripheral erythematous blush and holes in the papillary collagen.
The Diagnostic characteristics of SIAscopy versus dermoscopy for pigmented skin lesions presenting in primary care
Authors: J.Hunter, M.Moncrieff, P.Hall, F.Walter, J.Emery, S.Cotton, N.Burrows 2006.
Abstract:The Diagnostic characteristics of SIAscopy versus dermoscopy for pigmented skin lesions presenting in primary care (Poster). British Association of Dermatologists, UK, July 2006.
Spectrophotometric Intracutaneous Analysis (SIAscopy)
Authors: Paul J. Matts, Procter & Gamble, Egham, U.K. Symon D. Cotton, Astron Clinica, Cambridge, U.K.
Evaluation of the MoleMateTM training program for assessment of suspicious pigmented lesions in primary care
Authors: Annabel Wood[AU1], Helen Morris, BSc, PhD, Jon Emery, MB BChir, MRCGP, PhD, Per Hall[AU1], Symon Cotton[AU1], A Toby Prevost, MSc, PhD, Fiona M Walter MSc, MD, MRCGP
Abstract: Background: Pigmented skin lesions or ‘moles’ are a common presenting problem in general practice consultations: while the majority are benign, a minority are malignant melanomas. The MoleMateTM system is a novel diagnostic toolwhich incorporates spectrophotometric intracutaneous analysis (SIAscopy) within a non-invasive scanning technique and utilises a diagnostic algorithm specifically developed for use in primary care. The MoleMateTM training program is a short, computer-based course developed to train primary care practitioners to operate the MoleMateTM diagnostic tool.
Chromophore Mapping: a New Technique to Characterize Aging Human Skin, In Vivo
Authors: Paul J. Matts Ph.D1, Jeremy Carey Ph.D2 & Symon D. Cotton Ph.D2
